Efficacy of trabeculectomy in acute angle-closure glaucoma patients with sustained intraocular hypertension

Abstract

Objective To evaluate the efficacy of trabeculectomy in primary acute angle-closure glaucoma patients with sustained intraocular hypertension. Methods The data of 82 eyes of 79 patients of primary acute angle-closure glaucoma from Mar. 2016 to Oct. 2017 were analyzed retrospectively. The patients were divided into two groups: the observation group, 41 eyes of 40 patients, with IOP ≥40 mmHg and lasted for more than 3 days after conventional treatment and the control group, 41 eyes of 39 patients, with IOP<40 mmHg. The two groups were treated with trabeculectomy. The follow up time was 3 months. The surgical efficacy and postoperative complications were compared and analysed. Results The improved, unchanged and decreased rate of visual acuity in observation group at 3 months postoperatively were 78.05%, 17.07% and 4.88%, the difference were not statistically significant between the two groups (Z=1.620, P=0.110). The postoperative IOP of the two groups significantly decreased (P<0.05). The incidence of intraocular hypertension of observation group was higher significantly than control group at early stage after operation(χ2=4.100, P=0.042). The differences of IOP between the two groups was not statistically significant at 3 months postoperatively(t=1.309, P=0.194). Postopertive complication rate of observation group was 36.6%, and the control group was 7.3%.The difference between the two groups was statistically significant(χ2=10.250 P=0.001). Conclusion Trabeculectomy is safe and effective for primary acute angle-closure glaucoma patients with sustained intraocular hypertension, the complications should be treated actively. Key words: Glaucoma, angle-closure, acute, primary; Intraocular hypertension, sustained; Trabeculectomy