EFFICACY OF THE TOPICAL NASAL STEROID BUDESONIDE ON IMPROVING SLEEP AND DAYTIME SOMNOLENCE IN PATIENTS WITH PERENNIAL ALLERGIC RHINITIS

Abstract

Hughes K, Glass C, Ripchinski M, et al. Allergy. 2003;58:380–385 To determine the efficacy of topical nasal corticosteroids in the improvement of sleep and daytime somnolence among patients with perennial allergic rhinitis (PAR). Twenty-two subjects (18–65 years of age) with positive skin test responses to perennial allergens but not seasonal allergens were enrolled in the study. The study was a double-blind, placebo-controlled, crossover study that incorporated Balaam’s design. Patients were randomized to …