Efficacy of radiofrequency ablation performed under sevoflurane anesthesia in pediatric patients with ventricular premature beats

Abstract

Objective To evaluate the efficacy of radiofrequency ablation performed under sevoflurane anesthesia in the pediatric patients with ventricular premature beats(VPBs). Methods Twenty American Society of Anesthesiologists physical status Ⅰor Ⅱ pediatric patients, with non-organic heart disease and VPBs, aged 3-12 yr, weighing 19-53 kg, undergoing elective radiofrequency ablation, were divided into propofol group(Pro group)and sevoflurane group(Sev group)using a random number table.Anesthesia was induced with midazolam 0.05 mg/kg, sufentanil 0.3-0.5 μg/kg, propofol 2.5-4.0 mg/kg(in Pro group)and 8% sevoflurane(in Sev group). Supreme laryngeal mask airway was placed when eyelash reflex disappeared.Propofol 6 mg·kg-1·h-1 was intravenously infused in Pro group, and 2%-3% sevoflurane was inhaled in Sev group, and bispectral index value was maintained at 50-60.The frequency of VPBs developed was recorded before induction and at 1, 5 and 10 min after induction, and the recurrence was observed within 1 month after operation. Results Compared with that before induction, the frequency of VPBs developed was significantly decreased at 1, 5 and 10 min after induction in Pro group(P 0.05). The frequency of VPBs developed was significantly higher at 1, 5 and 10 min after induction in Sev group than in Pro group(P<0.05). The recurrent rate was 30% within 1 month after operation in Pro group, no recurrence was found in Sev group, and there was significant difference between Sev group and Pro group(P<0.05). Conclusion The efficacy of radiofrequency ablation performed under sevoflurane anesthesia is better than that performed under propofol anesthesia in the pediatric patients with VPBs. Key words: Anesthetics, inhalation; Child; Ventricular premature complexes; Catheter ablation