Efficacy of Platelet-Rich Plasma in Treatment of Periodontal Defects Following Surgical Extraction of Mandibular Third Molar

Abstract

Impacted mandibular third molar tooth has the potential to induce periodontal problems in the distal root of second molar tooth. Platelet-rich plasma (PRP) is an autologous biomaterial which has been used to enhance soft and hard tissue regeneration. The aim of the present study was to evaluate the effectiveness of PRP in management of periodontal pocket at the distal root of mandibular second molar tooth.49 patients with mesioangulary impacted third molar and periodontal problems at the distal part of adjacent second molar entered the study. The probing depth (PD) of distal root of second molar had to be more than 7.5 mm with clinical attachment loss (CAL) of more than 6 mm. In the study group PRP was applied at the osseous defect following third molar surgery while in control group nothing was used. PD, CAL, and alveolar bone loss (ABL) were re-evaluated after 6 months. After 6 months, study group had significantly higher attachment gain, lower PD, and lower ABL. Based on the results it could be concluded that PRP is an effective measure to enhance the regeneration of periodontal tissues following surgical extraction of mesioangulary impacted mandibular third molar tooth.