Abstract
In Reply.— Studies evaluating the efficacy of antibiotic prophylaxis for bacterial endocarditis in patients undergoing dental extractions are numerous, but studies dealing with the association between the peak serum concentrations achieved by the antibiotic used and the occurrence of postextraction bacteremia are lacking. It is questionable whether higher dosages than the dosages used in our study would have prevented the occurrence of postextraction bacteremia, because no relationship was found betwen the occurrence of postextraction bacteremia and postextraction serum penicillin concentrations.
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