Abstract
The purpose of this study is to investigate the analgesic effect of pranlukast hydrate (PH), a leukotriene receptor antagonist, in patients with postherpetic neuralgia (PHN). Twenty patients with PHN whose pain reached a plateau after 3 or more months received oral administration of PH at doses of 450 mg/day for 1 month. Visual analogue scales of rest pain, tactile allodynia, and paroxysmal pain were significantly reduced at 1 week, 2 weeks, and 1 month after the beginning of oral administration. The analgesic effect was better in patients suffering from PHN for 1 year or more than in the others. This suggests that leukotrienes may play a role in PHN.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
