Efficacy of Oral Immunotherapy with Colostrum on Preterm Very Low Birth Weight Infants

Abstract

Objective To explore the effect of oral immunotherapy of mother’ s colostrum on very low birth weight premature infants. Methods A total of 100 very low birth weight premature infants born in our hospital from June 2018 to June 2020 were enrolled and randomly divided into two groups. The experimental group （50 cases） received oral immunotherapy with colostrum, while the control group （50 cases） was treated with sterilized water for injection for daily oral care. A prospective controlled study was conducted to evaluate the length of hospital stay, hospitalization cost, enteral feeding time, length of antibiotic therapy, weight gain, incidence of NEC （Necrotizing enterocolitis） and nursing satisfaction of the two groups. Results There were statistically significant differences in the average length of hospital stay, hospitalization cost, enteral feeding time, length of antibiotic therapy, weight gain, incidence of NEC between the two groups （P Conclusion Oral immunotherapy of maternal colostrum can shorten hospital stay, reduce average daily hospitalization costs, shorten the length of antibiotic therapy, promote the growth and development of infants, reduce the incidence of NEC and improve parental care satisfaction, which is worthy of clinical promotion and application.