Efficacy of Open Anderson-Hynes Pyleloplasty in Congenital Unilateral Uretero-Pelvic Junction Obstruction in Terms of GFR in Children

Abstract

Background: Ureteropelvic junction obstruction” is defined as an anatomical abnormality that results in a functionally significant impairment of urinary transport from the renal pelvis to the ureter. Congenital UPJ obstruction results due to the presence of an aperistaltic segment of the ureter. Objective: To determine the efficacy of Open Anderson-Hynes pyeloplasty in unilateral congenital UPJO in terms of GFR Materials and Methods: This descriptive study of 139 patients of paediatric age group was conducted in the department of urology, Institute of Kidney Diseases, Peshawar from 24 July, 2019 to 24 July 2020. Patients with UPJO were operated. Efficacy of the procedure noted in term of GFR. Follow up ultrasound followed by nuclear scan was done after 2 months. Results: Out of 139 patients, 60(43.16%) were of age 5-10yrs and 79(56.83%) i.e. the majority were 11-15 yrs with mean and SDs of 11±2.37. The overall complication rate was 36.69%. The efficacy in terms of GFR improvement OR at least prevention of deterioration of renal function was recorded in 115 (82.73%) patients while 24 (17.26%) showed no efficacy Conclusion: Anderson-Hynes pyeloplasty is an effective procedure in terms of renal function improvement or to prevent GFR deterioration at the preoperative level in comparison to those not operated with gradual reduction in GFR.