Abstract
Mosquito-borne diseases are responsible for about one million death annually worldwide. Especially in endemic regions, using repellents is a practical approach to preventing such diseases. In this study, nanoemulsions containing carvacrol, cinnamaldehyde, thymol, and a mix of them were first prepared. The nanoemulsions were then gellified by adding carboxymethyl cellulose (CMC). Besides, viscosity and successful loading were investigated using viscometry and Attenuated Total Reflection-Fourier Transform InfraRed (ATR-FTIR) analyses. After that, the complete protection time of the nanogels compared to DEET (N, N-diethyl-meta-toluamide) was evaluated against the Anopheles stephensi. The repellent activity of commercial DEET (40% w/v) was 480 ± 30 min; interestingly, nanogel-containing carvacrol (2.4% w/v) showed 470 ± 17 min protection time. Besides, no significant difference was observed between nanogels containing cinnamaldehyde and a mix of them and DEET. The straightforward, repeatable preparation method and no need for advanced devices are some advantages of the developed nanogels. Results suggested that mentioned nanogels, especially carvacrol, could be considered novel natural repellents against A. stephensi and other species of vector mosquitoes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
