Efficacy of mixed adsorbent in ameliorating ochratoxicosis in broilers fed ochratoxin A contaminated diets

Abstract

The current study was conducted to evaluate the ability of mixed adsorbent (Na-MMT + YCW) for the preventing effect of Ochratoxin A in broiler productivity, biochemical parameters, histochemical changes and OTA residues. A total of 96 broiler chicks were grouped in three experimental and one control group (24 chicks in each group, 3 replicates each). Birds were fed basal dietary or that with Ochratoxin A and mixed adsorbent (Na-MMT + YCW) to determine the effect of this compound during mycotoxicoses. When compared with the controls, feed: gain (F/G) were significantly higher for broilers fed diets containing OTA alone (p < .05). No differences were found between the F/G of broiler chickens fed diets without OTA and those of chickens fed mixed adsorbent. The diet containing 2 mg OTA/kg without adsorbents added increased relative liver, kidney, spleen weights and decreased relative thymus, bursa weights. Alterations in the levels of serum TP, ALB, GLB, BUN and enzymatic activity of ALT, AST, ALP and GGT were observed for OTA diets, and moderate protection was provided by the sorbent. Supplementing mixed adsorbent group (Na-MMT + YCW) showed intestinal villus height and crypt depth similar to control chicks, and a significant reduction residue in livers and kidney tissue, as well as a significantly higher OTA content in the faeces compared with OTA- group were recorded. These results suggest that effects of OTA treatment were ameliorated when mixed adsorbent was used in the broiler chick diets.