Abstract
The influence of zearalenone on blood serum protein status and the feasibility of utilizing a modified clinoptilolite and esterified glucomannan to alleviate its harmful effects was examined in two trials, 31 and 29 days long, conducted on a total of 64 pigs (32 each) 60 days old, divided into four groups, each containing 8 pigs. Control groups (K) received noncontaminated feed, while experimental groups received feed supplemented with 3.84 mg/kg in the first trial and 5.12 mg/kg of zearalenone in the second trial. Pigs in the first experimental groups (O-I) were given feed with toxin only. Modified clinoptilolite in the amount of 0.2% and esterified glucomannan in the amount of 0.1% were introduced in contaminated feed of the second (O-II) and the third experimental groups (O-III) of both trials. With the use of contaminated feed, a declining trend of the A/G ratio was observed: decrease of albumin content and increase of globulin content on account of the _ globulin fraction. A decrease of the _ globulin fraction was detected at the same time. Total protein concentration was also lower. The application of adsorbents successfully alleviated harmful effects of the F-2 toxin on the affected biochemical parameters in blood serum.
Highlights
Uticaj zearalenona na status proteina krvnog seruma prasadi i mogu}nost upotrebe modifikovanog klinoptilolita i esterifikovanog glukomanana za ublaavanje njegovih {tetnih efekata ispitivan je kroz dva ogleda, u trajanju od 31 i 29 dana, izvedena na ukupno 64 prasadi (32 u svakom ogledu), 60 dana starih, podeljenih u 4 grupe, po 8 jedinki
Sumiraju}i sve navedeno, moe se zaklju~iti da se negativni efekti zearalenona na koncentraciju proteina krvnog seruma i relativnu zastupljenost njihovih frakcija, posebno g globulinske frakcije, mogu zadovoljavaju}e umanjiti upotrebom modifikovanog klinoptilolita i esterifikovanog glukomanana
Summary
Uticaj zearalenona na status proteina krvnog seruma prasadi i mogu}nost upotrebe modifikovanog klinoptilolita i esterifikovanog glukomanana za ublaavanje njegovih {tetnih efekata ispitivan je kroz dva ogleda, u trajanju od 31 i 29 dana, izvedena na ukupno 64 prasadi (32 u svakom ogledu), 60 dana starih, podeljenih u 4 grupe, po 8 jedinki. (2000) uo~ili su zna~ajno smanjenje sadraja ukupnih proteina krvnog seruma, sa promenom A/G odnosa kao posledicom rasta albumina na ra~un globulina kod prasadi koja je uzimala hranu kontaminiranu zearalenonom.
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