Abstract
Background Every year over 3.8 million people are dying of diabetes and its complications. Lifestyle intervention was suggested to have beneficial effects in preventing and reducing diabetes incidence. Especially interventions in patients with impaired glucose tolerance (IGT), who belong to a high risk group in developing diabetes, are supposed to be very effective. According to the evidence heirarchy, a 1a level of evidence is missing and therefore a systematic review verifying the efficacy of lifestyle intervention is needed.
Highlights
Every year over 3.8 million people are dying of diabetes and its complications
Overall 5663 patients were analyzed with primary follow-up time: India (3 yr), Japan (4 yr), Sweden (5 yr), Da Qing (6 yr), SIM (3 yr), DPP (5 yr), DPS (4 yr) and drop-out rate ranges from 5% to 28%
Diabetes incidence ranges from 3% to 46% in the intervention group and 9.3% to 67.7% in the control group
Summary
Every year over 3.8 million people are dying of diabetes and its complications. Lifestyle intervention was suggested to have beneficial effects in preventing and reducing diabetes incidence. Interventions in patients with impaired glucose tolerance (IGT), who belong to a high risk group in developing diabetes, are supposed to be very effective. According to the evidence heirarchy, a 1a level of evidence is missing and a systematic review verifying the efficacy of lifestyle intervention is needed
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