Abstract
The aim of this survey was to systematically overview clinical studies, published in the English literature, regarding the treatment of reflux oesophagitis with the newly developed proton pump inhibitor (PPI) lansoprazole, compared with other acid suppressant drugs. A total of 11 studies were identified in the literature and included in the overview; of these, four studies compared lansoprazole with ranitidine, one with famotidine and four with the PPI omeprazole. Two studies focused exclusively on the comparison of different dosages of lansoprazole. This overview showed that, with regard to healing rate and symptomatic relief, lansoprazole was superior to H2 receptor antagonists. Regarding healing rates and symptom response, lansoprazole was equal to omeprazole. The few data concerning long-term treatment indicated similar efficacy for the two PPIs. The tolerability of lansoprazole did not appear to be different to H2 receptor antagonists and omeprazole.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
