Efficacy of knee intra-articular medical ozone combined with sodium hyaluronate injection and thermal acupuncture in the treatment of knee osteoarthritis

Abstract

Objective To explore the efficacy of knee intra-articular medical ozone combined with sodium hyaluronate injection and thermal acupuncture in the treatment of patient with knee osteoarthritis. Methods Ninety patients with knee osteoarthritis were randomly divided into 3 groups (n=30): group A (ozone group), group B (sodium hyaluronate and thermal acupuncture group), and group C (ozone, sodium hyaluronate and thermal acupuncture group). Visual analogue scale (VAS) and modified MacNab methods were used to evaluate the clinical efficacy. Results VAS in group C was significantly lower than that in group A and B, and the difference was statistically significant (P 0.05). The efficacy of group C was significantly better than that in group A and B, and the difference was statistically significant (P<0.05). Conclusion Thermal acupuncture combined with knee intra-articular medical ozone and sodium hyaluronate injection to the knee cavity is an effective method in the treatment of knee osteoarthritis. Key words: Osteoarthritis, knee; Medical ozone; Hyaluronic acid; Thermal acupuncture