Abstract

<h3>To the Editor.—</h3> The drugs effective in post-kala-azar dermal leishmaniasis (PKDL) include parenteral administration of sodium antimony gluconate, amphotericin B, or pentamidine, of which sodium antimony gluconate is the treatment of choice.<sup>1</sup>The problem of giving a dose as high as 8.5 to 10 mL daily for the recommended period of 4 months is not only that the patient needs supervision but that it is difficult for the patient to endure. In an effort to find a suitable orally administered drug, we decided to assess the efficacy of ketoconazole (Nizoral tablets [200mgl, Janssen Pharmaceutica, Bombay, India) in PKDL, as this drug has recently proved useful in visceral leishmaniasis.<sup>2</sup> <h3>Subjects, Methods, and Results.—</h3> Four male patients with PKDL between 20 and 25 years of age were admitted into the study after obtaining their consent. The duration of the skin lesions varied from 2 to 4 years. Cutaneous examination

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