Efficacy of Ketamine in Combination with Four Common Analgesics on Some Hematological Factors of Broiler Chickens and #8194; and #8194; and #8194; and #8194; and #8194;

Abstract

In order to provide information on hematological and biochemical changes in broiler chickens during anesthesia after injecting of ketamine (35 mg/kg) combined with (A) tramadol (0.2 mg/kg), (B) midazolam (0.5 mg/kg), (C) hyoscine (0.04 mg/kg), and (D) atropine (0.05 mg/kg), forty numbers of broiler chickens were allocated to four equal groups. Each group received one of ketamine combinations in the pectoral muscles. Afterwards, values of packed cell volume (PCV), WBC, HLI (Heterophil/Lymphocyte Index), aspartate aminotransferase (AST), CoE, and glucose were determined at 0, 30, and 60 minutes post injection. Results revealed that injections of different combined drugs did not cause any specific effect on PCV values except in group D that showed significant increasing of PCV in time of 30 and 60. Clear leukocytosis was recorded at 60 min post injection groups A and C. Furthermore, spending time made an increase on heterophil populations compared to lymphocytes (P≤0.05). AST levels tended to rise in groups A, B and D during the experiment and a significant increase in AST activity was recorded in group B and D at 30 and 60 min post injection. The mean glucose and CoE concentrations decreased after injections in all groups; however, the concentration of CoE was increased at 60 min post injection in group B. In conclusion, using of ketamine in anesthesia can make changes effectively in several blood parameters of broiler chickens in combination with other drugs.