Abstract
Abstract: Kuchala (Strychnos nux-vomica) is spinal poison which is also classified as Upavisha in Ayurveda.Various poisons have been described in Ayurveda along with their antidotes. Mode of action of these antidotes is not mentioned in texts. In Ayurvedic literature According to Basavrajeeyam under the heading of Vish-Prativishani, Jambu (seed) have been described to be possessing antidote action which may act by some way to counter toxicity of Kuchala. It is necessary to verify the efficacy of these antidotes on scientific parameters so that it can be useful in emergencies. Objectives: To establish the action and mechanism of Jambu (seed) against toxic effects of Kuchala on albino wistar rats. Methods: albino wistar rats were selected as an animal model and antidote potential of Jambu (seed) against Kuchala is evaluated by measuring convulsions and histopathological reports of brain and spinal cord. Results: Jambu (seed) administration before Kuchala poisoning reduced the toxic effects of Kuchala such as convulsion and histopathological changes in brain and spinal cord. Conclusion: From this study, we can conclude that Jambu (seed) can resist the toxic effects of Kuchala up to some extent.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal for Research in Applied Science and Engineering Technology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
