Abstract
Background:Warts are benign cutaneous and mucosal epithelial proliferations caused by Human papilloma viruses (HPV).[1]Several therapeutic approaches have been used in treating warts like topical medication such as salicylic acid, trichloroacetic acid, podophyllin, podophyllotoxin, glutaraldehyde, formalin, imiquimod,5-uorouracil and ablative procedures and surgical excision. This study is designed to determine the efcacy of intralesional immunotherapeutic agent BCG vaccine in clearing warts. Materials and Methods: The study group comprised of 20 cases of multiple recalcitrant cutaneous warts. Ethical clearance was sought and informed consent was obtained from all patients.The wart with longer duration and largest size was selected for this procedure. 0.1ml of BCG vaccine was injected intralesionally into the wart and was repeated every 3 weeks till complete clearance of the warts or for a maximum of 9 weeks. Results: After completion of 3 sittings at an interval of 3 weeks we observed the complete response in common warts , palmar warts and plantar warts was 64.5% , 58% and 40% respectively. Conclusion: Our study showed that intralesional BCG injection was safe and efcacious in the treatment of multiple recalcitrant cutaneous warts.
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