Abstract

Introduction: To evaluate the usefulness of homeopathy for the treatment of PCOS through a literature review and to develop a strategy for future research. Method: A comprehensive search was done in electronic databases, including general medical databases MEDLINE, CENTRAL, Science Direct, specialised database for homeopathy CORE-Hom, CAM databases LILACS Chiro ACCESS, AYUSH Research Portal, Google Scholar, Research gate net, clinical trial registry, aimed to target the available literature of observational studies, randomized trials, controlled trials, case reports on PCOS in homeopathy and limited to the English language. The inclusion criteria are the studies with a full-text present in mentioned databases, studies with experimental or quasi-experimental designs published in peer-reviewed or partial peer-reviewed journals and studies with humans as their samples. Result: A literary search through databases helped to identify a few significant studies, such as one placebo-controlled trial, one comparative clinical study, one retrospective study, three clinical studies, and nine case reports. A retrospective study showed positive results for the role of homeopathic medicines in PCOS. The placebo-controlled trial showed a difference in outcome between the two groups. The verum group showed a positive effect in the regularization of menses. The comparative clinical study showed that both homeopathic medicines (Cal. carb, Lycopodium) appeared to be effective. Three clinical studies showed the effectiveness of homeopathic medicines in improving and curing PCOS. Nine case reports showed a positive effect of homeopathy in improving PCOS, out of which three cases showed positive outcomes also in infertility with PCOS. Conclusion: The results showed that Homoeopathy has positive effects on the management of PCOS in women. In the future, high-quality randomized controlled trials (RCT), comparative studies of homeopathy with conventional therapy, and in-vitro and animal model studies will be required to support the effectiveness of homeopathic therapeutics in PCOS.

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