Efficacy of high frequency jet ventilation via nasopharyngeal catheter in assissting ventilation in patients with OSAHS undergoing gastroscopy

Abstract

Objective To investigate the efficacy of high frequency jet ventilation via the nasopharyngeal catheter in assissting ventilation in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) undergoing gastroscopy. Methods Eighty patients with OSAHS of both sexes, aged 40-64 yr, weighing 65-99 kg, of American Society of Anesthesiologists physical status Ⅰ or Ⅱ, with an apnea-hypopnea index 20-40 events/h, scheduled for elective painless gastroscopy, were divided into control group and test group using a random number table, with 40 patients in each group.In control group, a nasopharyngeal catheter 6.0-7.0 mm in internal diameter was inserted, and oxygen was inhaled at 4 L/min through the catheter.In test group, a nasopharyngeal catheter 4.0 mm in internal diameter was inserted, and a high frequency jet ventilator was connected (inspiratory/expiratory ratio 1.0∶1.5, frequency 150 bpm, peak pressure 0.4 kPa, tidal volume 180 ml). Anesthesia was maintained with propofol in both groups.The occurrence of hypoxemia during ventilation, and peak value of partial pressure of end-tidal CO2 before induction of anesthesia and during ventilation, and occurrence of chin lift, mask ventilation, and epistaxis after insertion of the catheter during operation were recorded. Results Compared with control group, the incidence of hypoxemia, peak value of partial pressure of end-tidal CO2 during ventilation, and incidence of chin lift, mask ventilation and epistaxis during operation were significantly decreased in test group (P<0.05). Conclusion High frequency jet ventilation via the nasopharyngeal catheter can be safely and effectively used to assisst ventilation in patients with OSAHS undergoing gastroscopy. Key words: High-frequency ventilation; Sleep apnea, obstructive; Gastroscopy