Efficacy of glycolic acid for the removal of calcium hydroxide from simulated internal Resorption cavities.

Abstract

This study evaluated the efficacy of 5% and 10% glycolic acid solutions for the removal of calcium hydroxide medicament from artificial internal resorption cavities. A total of 170 human maxillary premolars were selected and artificial internal resorption cavities were prepared using round burs and 37% orthophosphoric acid in the apical third of the root halves. Entire canal and resorption cavity were filled with calcium hydroxide paste. Then, the specimens were assigned to 2 control groups or ten experimental groups according to the irrigating solutions used for medicament removal with and without activation with ultrasonic energy as following: 5% glycolic acid, 10% glycolic acid, 17% EDTA, and 10% citric acid and distilled water. The resorption cavities were examined under different magnifications using stereomicroscopy and scanning electron microscopy (SEM). The calcium hydroxide remnants in the resorption cavity were scored by 2 evaluators using a 4-scoring scale. The data were analyzed with Kruskal-Wallis H tests with 5% significance threshold. There was no significant difference regarding the distribution of removal scores among non-activated solutions (P > 0.05). In activated groups, 10% glycolic acid irrigation removed significantly more amount of calcium hydroxide than EDTA and distilled water (P < 0.05). No significant difference was found between the efficacy of 10% glycolic and citric acid (P > 0.05). Citric acid, 5% glycolic acid, and EDTA showed similar removal scores (P > 0.05). Passive ultrasonic irrigation significantly improved calcium hydroxide removal scores in 10% glycolic acid, citric acid, and EDTA groups (P < 0.05). The SEM examination revealed that the specimens that were scored 0 are not entirely free of calcium hydroxide remnants. Concentration of 10% glycolic acid removed significantly more calcium hydroxide paste from resorption cavities than EDTA when used with passive ultrasonic irrigation. Although passive ultrasonic irrigation favored medicament removal in all irrigating solutions, complete elimination of medicament remnants was unattainable. This study showed the improved efficacy of ultrasonically activated 10% glycolic acid in removing the calcium hydroxide medicament from the internal resorption cavity.