Efficacy of EPBD lithotomy and EST lithotomy on common bile duct stones and the effects on serum levels of inflammatory factors

Abstract

Objective To investigate the surgical efficacy of endoscopic papillary balloon dilatation (EPBD) and endoscopic sphincterotomy (EST) on common bile duct stones (CBDS) and the effects on the levels of serum amylase (AMY), C-reactive protein (CRP) and white blood cell (WBC). Methods Eighty CBDS patients admitted in Pinglu People’s Hospital from August 2012 to August 2015 were selected for the study, and they were divided into EST group and EPBD group according to the random number table method, with 40 cases in each group. The operation related conditions, the levels of serum AMY, CRP and WBC, and the incidence of short-term and long-term complications were compared between the two groups. Results There was no significant difference in the operative time, once stone removal success rate, stone removal success rate and hospital stay between the two groups (P>0.05); and the medical expenses in EST group (19 400±1 100 yuan) was significantly lower than that in EPBD group (22 200±1 300 yuan), P 0.05). The short-term total incidence rate of complications was 30.00% in EST group and 37.50% in EPBD group (P>0.05), and the long-term total incidence rate of complications was 7.50% and 0 respectively in the EST group and EPBD group (P>0.05). Conclusions EST lithotomy can have big body inflammatory stress response, but its stone removal effect and surgical safety are equal to the EPBD lithotomy, and the surgical methods should be chosen according to the specific circumstances of the patient. Key words: Endoscopic papillary balloon dilatation; Endoscopic sphincterotomy; Common bile duct stones; Complications; Efficacy