Efficacy of endovascular embolization using combination of Embosphere microspheres and mechanical coils in treatment of massive hemoptysis

Abstract

Objective: To evaluate the clinical efficacy of bronchial artery embolization (BAE) using combination of Embosphere microspheres and mechanical coils in treatment of massive hemoptysis. Methods: During the period from October 2014 to January 2016, a total of 52 patients with massive hemoptysis who had failed to respond to medical management received BAE, among these, the clinical efficacy of massive hemoptysis patients treated with Embosphere microspheres (n=25, group EM) was compared with those treated with combination of Embosphere microspheres and mechanical coils (n=27, group MC) . All patients were followed up for 1 year. Results: BAE was successfully accomplished in all 52 patients with an effective rate of 96.15% for bleeding-cessation within 24 h. In each group there was 1 case of hemoptysis, without statistical significance (P>0.05) . Recurrence of hemoptysis within 1 year after BAE was seen in 9 patients (nEM=7, nMC=2, 8/52, 17.31%) . Recurrence of hemoptysis within 3 months after BAE was found in 1 patient in both EM and MC groups (P>0.05) . MC group had a lower recurrence rate than EM group during the follow-up period of 3~12 months after the procedure (3.7% vs 24%, P<0.05) . Conclusions: Combination of Embosphere microspheres and mechanical coils can efficient improve the metaphase and long-term efficacy of BAE, and reduce the recurrence of hemoptysis. Key words: Embosphere microspheres; Mechanical coils; Combined embolization; Bronchial artery embolization; Efficacy