Efficacy of early laparoscopic surgery for the treatment of gallstone-induced acute pancreatitis

Abstract

Objective To evaluate the efficacy, safety and stress response of early laparoscopic surgery for biliary acute pancreatitis. Methods The data of 92 cases of biliary acute pancreatitis from October 2013 to April 2017 were analyzed and randomly divided into early group (early laparoscopic surgery, 46 cases) and delayed group (delayed laparoscopic surgery, 46 cases). SPSS22.0 was used for analysis, the data of operative index, cortisol and epinephrine were expressed by (±s). The paired t test was used before and after the treatment in the group, and the independent sample t test was used between the groups. The total effective rate, the incidence of complications and the recurrence rate were compared with chi-square test. P<0.05 was statistical significance for differences. Results The intraoperative blood loss, operative time, hospital stay and postoperative recovery time in the e arly group were lower than those in the delayed group (P 0.05). The levels of cortisol and epinephrine were higher than those before the treatment in the two groups (all P<0.05), but the degree of stress reaction in the early group was lower than that of the delayed group(P<0.05). Conclusion Early laparoscopic surgery for biliary acute pancreatitis has a shorter operative time, less intraoperative blood loss, and a low degree of stress response. The treatment effect is better than delayed laparoscopic surgery and it is worthy of popularization and application. Key words: Pancreatitis; Cholecystectomy, laparoscopic; Safety