Abstract

Objectives: To determine the efficacy of double volume exchange transfusion in term neonates with hyperbilirubinemia due to ABO incompatibility. Materials and Methods: This was a descriptive case series study conducted in the Neonatal Unit, Department of Pediatrics, Sheikh Zayed Hospital, Rahim Yar Khan from 30-09-2016 to 29-12-2017. Results: Total cases were 87, out of which 47 (54.02%) were males with a mean age of 4.32±1.51 days. The efficacy of double exchange transfusion was seen in 28 (32.18%) cases. Conclusion: The efficacy of double volume exchange is seen in 28 (32.18%) out of 87 cases and it is significantly high in cases when the exchange is done within the first 3 days of birth (p= 0.01). Keywords: ABO incompatibility, hyperbilirubinemia, double volume exchange transfusion.

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