Efficacy of different surgical approaches on anterior skull base and saddle area lesions

Abstract

Objective To analyze the effect of different surgical approaches on anterior skull base and saddle area lesions. Methods Seventy-one patients with anterior skull base and saddle area lesions who were randomly selected between January 2012 and January 2015, of them, 38 cases underwent trans-eyebrow approach surgery were selected as observation group, and 33 cases underwent trans-forehead approach surgery were selected as control group. The degree of tumor resection, surgical time, postoperative complications and the relief of clinical symptoms and improvement of quality of life were compared between the two groups. Results There was no significant differences in the degree of tumor resection or clinical symptoms (headache, visual impairment, endocrine symptoms) between the two groups (P>0.05). The differences in surgical time, intraoperative blood loss and incidence of postoperative complications between observation group [(180.4±18.8) min, (174.7±58.3)ml, 5.3%] and control group [(240.3±32.1) min, (265.73±83.24) ml, 21.2%] were significant (P 0.05). Conclusions Both of trans-eyebrow and trans-forehead approach surgery can significantly relieve the clinical symptoms in patients with anterior skull base and saddle area lesions and improve quality of life. However, the surgical time and hospitalization time of the former is shorter, with less intraoperative blood loss and fewer postoperative complications. Key words: Anterior skull base and saddle area lesions; Trans-eyebrow approach; Trans-forehead approach