Abstract

ObjectivesThe objective of this study was to compare the efficacy in reducing hypersensitivity in molar incisor hypomineralization (MIH)-affected molars immediately and over 8 weeks combining a single in-office application and a homed-based program with desensitizing products containing 8% arginine and calcium carbonate.Materials and methodsNineteen children with at least one MIH-affected molar with hypersensitivity were included. Hypersensitivity was assessed with an evaporative (air) stimulus and a tactile stimulus. Each child received a single in-office treatment with a desensitizing paste containing 8% arginine and calcium carbonate (elmex Sensitive Professional desensitizing paste), followed by 8 weeks of brushing twice daily with a desensitizing toothpaste containing 8% arginine, calcium carbonate with 1450 ppm fluoride (elmex Sensitive Professional toothpaste), using the elmex Sensitive Professional toothbrush. Additionally, the corresponding mouthwash (elmex Sensitive Professional mouthwash) was used. Clinical assessments were made at baseline, immediately after the in-office treatment and after 1, 2, 4 and 8 weeks of brushing twice daily.ResultsFifty-six molars with an air blast hypersensitivity score of 2 or 3 (Schiff Cold Air Sensitivity Scale) were included. Application of the desensitizing paste decreased hypersensitivity significantly immediately and throughout the 8 weeks recalls (p < 0.001).ConclusionsIn conclusion, 8% arginine and calcium carbonate were able to reduce hypersensitivity successfully during this 8-week trial.Clinical relevanceHypersensitivity is a major complaint in patients with MIH. This is the first study evaluating the desensitizing effect of a desensitizing paste containing 8% arginine and calcium carbonate in patients with MIH.

Highlights

  • The term molar incisor hypomineralization (MIH) was introduced in 2001 to describe the clinical picture of enamel hypomineralization of systemic origin affecting one or more first permanent molars that are associated frequently with affected incisors [1]

  • Clinical relevance Hypersensitivity is a major complaint in patients with MIH

  • Patients affected by MIH present several clinical problems, including rapid wear, enamel loss, increased susceptibility to caries, loss of fillings, and most of all, severe hypersensitivity often resulting in severe discomfort [5]

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Summary

Introduction

The term molar incisor hypomineralization (MIH) was introduced in 2001 to describe the clinical picture of enamel hypomineralization of systemic origin affecting one or more first permanent molars that are associated frequently with affected incisors [1]. Its etiology remains unknown [2]. It has been suggested that MIH is a genetic condition based on its prevalence [3] and that childhood illness is likely to be associated with MIH [4]. Patients affected by MIH present several clinical problems, including rapid wear, enamel loss, increased susceptibility to caries, loss of fillings, and most of all, severe hypersensitivity often resulting in severe discomfort [5]. Behavior management problems and even dental fear

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