Abstract
Abstract In the present study, antimicrobial activities of the crude extracts of the plant Clitoria ternatea were tested against the urinary tract infection causing pathogen Proteus mirabilis. Initially, 63 clinical samples from different age groups were collected for evaluating the urinary tract infection. Then, the clinical samples were examined for the presence of Proteus mirabilis bacterium by assessing morphological, biochemical, and cultural characteristics. To assess the zones of inhibition for various antibiotics towards Proteus mirabilis, disc diffusion method involving standard antibiotic discs was used. The antibacterial activities of antibiotics against Proteus mirabilis showed that ciprofloxacin, gentamycin and tetracycline exhibited better zones of inhibition. Further, the extracts from the leaves of Clitoria ternatea were prepared with different solvents such as acetone, isopropyl alcohol and petroleum ether and the extract yield was higher in acetone than the other two solvents. The highest antibacterial activity was observed for acetone and the lowest antibacterial activities were observed for isopropyl alcohol, and petroleum ether extracts against Proteus mirabilis. In addition, phytochemical analysis revealed the presence of several bioactive compounds.
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