Efficacy of consumption of whole and fractionated pulses on plasma lipids in diet‐induced dyslipidemic Syrian hamsters (829.19)

Abstract

The objective was to examine effects of whole and fractions of pinto beans and peas on diet induced dyslipidemia. Hamsters were randomly assigned to consume high fat diet (n=12 each) including control (CON); bean starch (BS); bean fibre (BF); whole bean (WB); cooked whole bean (CWB); inner pea fibre (IPF); pea hull fibre (PHF); pea protein isolate (PPI); pea protein concentrate (PPC); or whole pea (WP) for 4 wk. Reduced feed intake (FI) and body weight gain (BWG) were observed with WB (FI: p=0.030; BWG: p<0.001), BS (FI: p=0.041; BWG: p<0.001) and BF (FI: p=0.037; BWG: p<0.001) compared to CON. However, both FI and BWG did not differ between CWB and CON. Plasma total, HDL and non‐HDL cholesterol, triglyceride and glucose concentrations were lower (p<0.05) in CWB, WB, BS and BF compared to CON. Furthermore, no changes in plasma lipids were observed with BF and BS compared to WB. No changes in FI, BWG and plasma glucose and lipid profile were observed with any of the peas supplemented groups compared to CON. A positive hemagglutination was observed with raw WB, BS and BF, but not CWB, against rabbit erythrocytes. Data suggest that, while whole and fractionated peas failed to alter plasma lipids and glucose levels, fractions and whole beans possess lipid lowering and hypoglycemic effects in hamsters, but must be cooked prior to intake. Results indicate that bean consumption can improve blood lipids and reduce cardiovascular disease riskGrant Funding Source: Supported by Pulse Canada; Agriculture and Agri‐Food Canada