Abstract
We recommend a new kind of spray made from eight kinds of traditional Chinese medicine, we aimed to investigate the safety and clinical efficacy of combined traditional Chinese medicine spray (TCMS) with premature ejaculation desensitization therapy (PEDT) for the treatment of primary premature ejaculation (PPE). A total of 90 patients with PPE were randomly assigned to receive TCMS, PEDT monotherapy or TCMS plus PEDT combination therapy for 6 weeks. Intravaginal ejaculation latency time (IELT) and Chinese index of sexual function for premature ejaculation (CIPE-5) were measured to evaluate the effect of each treatment. Eighty six (86) participants completed the study voluntarily. Both IELT and CIPE-5 in these three groups increased after treatment when compared with baseline levels (p< 0.01). IELT and CIPE-5 after treatment in TCMS plus PEDT group were significantly higher than those in the other two groups (both p <0.05). Additionally, clinical efficacy in TCMS plus PEDT group (89.7%) was significantly higher than in TCMS (65.5%) and PEDT group (67.9%) (p< 0.01). The self-made TCMS was safe and effective for the treatment of PPE, a combination of TCMS and PEDT therapy was more effective than the TCMS or PEDT monotherapy.
Highlights
Premature ejaculation (PE) is a very common male sexual dysfunction with prevalence rates of 20–30%1,2
While the pathophysiology of primary premature ejaculation (PPE) is not fully understood, nowadays it is clear that both organic and psychosocial factors play a role in the etiology[4], glans penile hypersensitivity and hyperexcitability is the general reason for PPE5-7
Employing a cutoff score of 18, the sensitivity of CIPE5 was 97.60%, the specificity 94.74%29. This present study showed that both Intravaginal ejaculation latency time (IELT) and CIPE-5 significantly increased in the three groups, whereas the increase in traditional Chinese medicine spray (TCMS) plus premature ejaculation desensitization therapy (PEDT) group was more than that in other two groups (Table 3)
Summary
Premature ejaculation (PE) is a very common male sexual dysfunction with prevalence rates of 20–30%1,2. While the pathophysiology of primary premature ejaculation (PPE) is not fully understood, nowadays it is clear that both organic and psychosocial factors play a role in the etiology[4], glans penile hypersensitivity and hyperexcitability is the general reason for PPE5-7. Studies found that patients with PPE have more dorsal nerves of the penis than healthy adults, this abnormal distribution of dorsal nerves possibly leads to glans penile hypersensitivity, lowering the African Health Sciences. @ 2017 Cui et al; licensee African Health Sciences Therapy of reducing glans penile hypersensitivity should be effective for the treatment of PPE
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