Efficacy of Cold Renal Perfusion Protection for Open Complex Aortic Aneurysm Repair: A Meta-Analysis

Abstract

Open surgical repair of complex aortic aneurysms has been associated with a risk of acute kidney injury, leading to significant morbidity and mortality. Cold renal perfusion (CRP) with 4°C crystalloid fluids during open repair is a method to reduce renal injury during repair. A meta-analysis assessing CRP for open repair of complex aortic aneurysms was performed. Complex aneurysms were defined as those requiring at least a suprarenal clamp site and included juxtarenal, suprarenal, and thoracoabdominal aortic aneurysms.