Abstract
BackgroundTo evaluate the efficacy of tulsi extract mouthrinse in reducing halitosis as compared to chlorhexidine and hydrogen peroxide mouthrinses using spectrophotometric analysis.Material and MethodsIt was a parallel, single center, double blinded randomized controlled trial of 15 days duration. A total of 300 participants were screened, out of which 45 subjects those fulfilled inclusion criteria of age range 17-35 years were included in the trial. The participants were randomly provided with tulsi, hydrogen peroxide or chlorhexidine mouthwashes (control group) to use 10 ml twice daily for 15 days. Clinical measurements were taken at baseline and 15 days using arbitrary 0-5 scale for organoleptic odor assessments, spectrophotometric analysis for Volatile Sulphide Compounds (VSCs) from saliva samples, Löe & Silness gingival index and Silness & Löe plaque index.ResultsAfter intervention, organoleptic, VSCs, gingival and plaque scores showed statistically significant decrease in all the three study groups. The mean percentage reduction in VSC and organoleptic scores was significantly greater in chlorhexidine and hydrogen peroxide groups than in the tulsi group and the mean percentage reduction in plaque and gingival scores was significantly greater in chlorhexidine group than in hydrogen peroxide and tulsi group.ConclusionsTulsi may not have the efficacy of chlorhexidine and hydrogen peroxide mouthrinses. But, Tulsi is effective in reducing halitosis, plaque and gingivitis and with its lack of side effects & cost effectiveness, can be an effective & economic tool to deal with halitosis. The spectrophotometric technique appears to be a promising method for evaluation of oral malodor. Key words:Halitosis, tulsi mouthwash, chlorhexidine, hydrogen peroxide, spectrophotometric analysis.
Highlights
Halitosis is one of the society’s oldest and most troublesome social maladies
Comparison between the three study groups showed no significant difference at the baseline in terms of means of Volatile Sulphide Compounds (VSCs)’ scores, organoleptic scores, plaque scores and gingivitis scores (Table 1)
The results showed that there was a statistically significant difference in the mean VSC, organoleptic, plaque and gingival scores from baseline to day 15
Summary
Halitosis is one of the society’s oldest and most troublesome social maladies It has been recorded in literature since 1500 B.C. It has been recorded in literature since 1500 B.C It is commonly described as bad breath, unpleasant or nasty smell coming from the mouth. In this study a newer technique, “spectrophotometric analysis from headspace of suspended saliva” was attempted to assess the reduction in mercaptans levels following the use of chlorhexidine, hydrogen peroxide and tulsi mouthrinse [17]. The aim of the present study was to determine the effectiveness of tulsi extract mouthrinse, in reducing halitosis as compared to Chlorhexidine and hydrogen peroxide mouthrinses, using spectrophotometric analysis. To evaluate the efficacy of tulsi extract mouthrinse in reducing halitosis as compared to chlorhexidine and hydrogen peroxide mouthrinses using spectrophotometric analysis. The spectrophotometric technique appears to be a promising method for evaluation of oral malodor
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