Abstract
Methods: The frequency of infection with specific microorganisms was compared between native valve and device related endocarditis, using infective endocarditis admissions in a New South Wales state wide database between 2000 and 2006. Results: Methicillin resistant Staphylococcus aureus was more significantly associatedwith device related infection (p= 0.008). Culture negative endocarditis was more significantly associated with native valve endocarditis (p= 0.02). Amongst patients with native valve endocarditis, MSSA was more significantly associated with IVDU (0.0002) and strep viridans was significantly associated with community acquired infection. Pathogens Native Valve Endocarditis (%) [N= 1393] Device Related Endocarditis (%) [N= 60] p (Chi sq.) Negative Blood Culture 19.7 6.7 0.02 Methicillin sensitive S. aurues (MSSA) 26.1 33.3 0.2 Methicillin resistant S. aureus (MRSA) 6.3 15.0 0.008 S. epidermidis 5.2 3.3 0.5 Streptococcus viridans 23.8 21.7 0.1 Enterococcus 9.0 6.7 0.5 Pneumococcus 0.9 1.7 0.5
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