EFFICACY OF CARDIAC RESYNCHRONIZATION THERAPY IN HEART FAILURE AT HUE UNIVERSITY HOSPITAL

Abstract

Background: Cardiac resynchronization therapy is one of new methods used to treating patients with heart failure who have ventricular dyssynchrony. Objectives: 1. To study clinical, laboratory characteristis of heart failure patients with ventricular dyssynchrony. 2. To study the efficacy of cardiac resynchronization therapy in treating such group of patients. Materials and method: From February 2009 to February 2011, we implanted biventricular pacemakers at Hue University Hospital for 15 patients who had NYHA class III and IV heart failure and had been treated with optimal medical therapy, LVEF ≤35%, QRS duration ≥ 120ms. Result: 14/15 cases succeeded, cardiac function improved after 1 year follow – up of biventricular pacemaker implantation, with significantly increased EF, decreased LVIDd, PAPs. At the cut off of EF <30%, the rate of patients with EF <30% declined chronologically (1 year of follow – up). Functional symptoms improved overtly according to NYHA class. The choice of A-V delay and V-V delay is very important. Optimal A-V delay and V-V delay after programming were (152±8.33)ms and (26.33±6.31)ms, retrospectively. Conclusion: Cardiac resynchronization therapy is effective in improving heart failure patients with ventricular dyssynchronization.