Abstract
Treatment with plasma-derived C1 esterase inhibitor (C1-INH) concentrate is well established for acute hereditary angioedema (HAE) attacks. However, data on the efficacy of C1-INH for cutaneous edema of HAE compared to placebo is limited, therefore the effect of C1-INH in cutaneous edema in the I.M.P.A.C.T.2 study was compared to historical untreated controls.
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