Efficacy of autologous blood withdrawal-reinfusion for scoliosis surgery: a retrospective analysis based on propensity score matching

Abstract

Objective To evaluate the efficacy of autologous blood withdrawal-reinfusion for scoliosis surgery.Methods Six hundred and seventy-seven patients of both sexes,aged 7-64 yr,weighing 20-83 kg,who underwent scoliosis surgery from August 2007 to November 2013,were randomly divided into 2 groups according to whether or not autologous blood withdrawal-reinfusion was applied:control group (group C,n =474) and autologous blood withdrawal-reinfusion group (group WR,n =203).Propensity score matching analysis with preset caliper width was used.A total of 181 matched pairs were selected from the patients.The intra-operative and post-operative requirements for allogeneic red blood cell (RBC) and plasma transfusion and peri-operative blood transfusion-related cost were recorded.Results Compared with group C,the intraoperative requirement for allogeneic RBC transfusion was siguificantly decreased,the cost was increased,and no significant change was found in perioperative requirements for allogeneic RBC and plasma transfusion in group WR.Conclusion Although autologous blood withdrawal-reinfusion can reduce the intraoperative requirement for allogeneic RBC transfusion,it can not reduce the perioperative requirement for allogeneic blood transfusion,and increases the cost of perioperative blood transfusion when used for scoliosis surgery,thus providing no significant value clinically. Key words: Blood transfusion, autologous; Scoliosis; Propensity score