Abstract
BackgroundTo evaluate the safety and efficacy of a bandage contact lens for alleviating dry eye discomfort after phacoemulsification.MethodsIn this prospective, controlled study, 60 age-related cataract patients with mild Meibomian gland dysfunction (MGD) were randomized to treatment with an ocular bandage contact lens (BCL) (n = 30) or to an untreated control group (n = 30) after phacoemulsification and intraocular lens implantation. The Ocular Surface Disease Index (OSDI) questionnaire, evaluation of subjective symptoms and evaluation of the best-corrected visual acuity (BCVA) were conducted preoperatively and postoperatively on days 1, 7, 14, 30 and 90. The tear breakup time (TBUT), Schirmer test with anesthesia, and fluorescein staining scores were measured preoperatively and postoperatively on days 7, 14, 30 and 90.ResultsThere were no significant differences with respect to the BCVA between the groups at any time point. For the comparison of the OSDI, subjective evaluation scores, TBUT and fluorescein staining, statistically significant improvements were noted in the BCL group, especially on days 7 and 14 (P < 0.001, P < 0.001; P = 0.031, P = 0.009; P = 0.021, P = 0.028; and P = 0.03, P = 0.032, respectively). The Schirmer test results did not significantly change postoperatively.ConclusionsA BCL can improve tear film stability and lessen dry eye discomfort immediately after phacoemulsification.Trial registrationCurrent Controlled Trials ChiCTR-INR-16008863 (Date of registration: 20 July 2016).
Highlights
To evaluate the safety and efficacy of a bandage contact lens for alleviating dry eye discomfort after phacoemulsification
The purpose of this study was to evaluate the efficacy of bandage contact lens (BCL) in alleviating dry eye signs and symptoms after cataract surgery, especially for age-related cataract patients with Meibomian gland dysfunction (MGD)
If patients underwent surgery on both eyes, only the first eye was evaluated for this study, i.e., 60 eyes of 60 patients were included in the study
Summary
To evaluate the safety and efficacy of a bandage contact lens for alleviating dry eye discomfort after phacoemulsification. Most patients obtain excellent postoperative distance visual acuity, some complain of continued ocular discomfort, such as a burning sensation, fatigue, foreign body sensation and other dry eye symptoms, which greatly reduce visual quality [1,2,3,4,5]. Many factors can cause dry eye after cataract surgery, Meibomian gland dysfunction (MGD) is one important cause that cannot be ignored [6]. Some patients experience severe dry eye symptoms due to decreased Meibomian gland function, ocular surface inflammation [10], and other causes, which may aggravate the visual symptoms and decrease patient quality of life
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