Abstract
We recently reported the efficacy of a novel TCM therapy – consisting of both oral and topical medications – against AD [1]. Building on these results, we developed improved galenic formulations of two multi-component TCM extracts (overall 13 drugs) for purely topical application. All drugs were powdered and extracted in of boiling water for 5h. Extract 1 was formulated as an herbal soap (1) with anti-inflammatory activity and used for washing the affected areas. For extract 2, three distinct galenic formulations were developed, namely a lotion (2A) with high skin penetrating activity and fast-acting antipruritic effect; a gelatinous jelly (2B) favorable for the treatment of scratching and rupture scars; and a Vaseline based ointment (2C) with long-time activity due to retarded skin penetration and resulting moisturizing and skin protective action for the treatment of dry skin and ulcers.
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