Efficacy of a Tailored COMET Protocol Combined with Medication on Vibratory Perception and SkinConductance in Diabetic Neuropathy- A Protocol for Randomized Controlled Trial

Abstract

This research attempts to evaluate the effectiveness of a customized COMET protocol in conjunction with medicine for the treatment of diabetic neuropathy, with vibratory perception and skin conductance being the main focus. Participants will be allocated to either the intervention group, which will get the customized COMET protocol and medicine, or the control group, which will receive standard medication alone, in a randomized controlled trial. Validated measurement instruments will be used in the trial to evaluate variations in skin conductance and vibratory perception both at baseline and during the course of the investigation. Strict adherence to ethical rules will guarantee the safety and well-being of participants. This study intends to provide important insights into the holistic management of diabetic neuropathy by examining the effects of the customized COMET protocol in conjunction with medication on vibratory perception and skin conductance. This could result in better treatment plans and an improvement in the quality of life for those who are affected. CTRI Reference Number CTRI/2023/07/055366,https://ctri.nic.in/Clinicaltrials/rmaindet.php?trialid=89691&EncHid=88073.73654&modid=1&compid=19,20/07/2023