Abstract
Purpose - To assess experimentally the hemodynamic performance and diverting capacity of a new permanent filtering device in (the Diverter) to be implanted at the carotid bifurcation. It is designed to divert emboli away from the internal into the external carotid artery to prevent embolic stroke. Methods - Flow visualization in a compliant transparent model of the carotid bifurcation (Figure 1) was used to study varying ICNECA flow ratios and physiological waveforms. Rigid emboli-like particles and soft-sticky emboli made of clotted blood (predefined cutoff sizes ranging (if 0.45–3mm) were driven towards the filter via computer-controlled pumps.Figure 1: Caption Not Available.Results - All particles larger than the filtering pores, both soft-sticky and rigid emboli, were diverted into the ECA and none passed into the filtered ICA ostium. Extreme ICNECA flow ratios, geometrical changes to the ICNECA angle or to the radius of the CCA curvature did not result in any emboli trapping. Emboli were only temporarily and rarely trapped under extreme non-physiological steady flow conditions. This permanent arterial filtration device was found to be efficacious in emboli diversion, and is potential novel therapy for embolic disease.
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