Efficacy of 2D/3D HyCoSy with new contrast medium lignocaine and saline comparing with HSG - A single centre prospective study

Abstract

Tubal patency significantly impacts female infertility, with a substantial portion of cases linked to tubal damage. This hinders gamete and embryo transfer. While laparoscopic chromo-pertubation is the gold standard, its invasiveness prompts the search for alternatives. Common methods for assessing tubal health are Hysterosalpingography (HSG) and Hysterosalpingo Contrast Sonography (HyCoSy).The objective of this study is to assess and compare the efficacy of a budget-friendly 2D/3D HyCoSy method using a unique contrast agent with traditional HSG for diagnosing tubal patency in women with infertility issues.A prospective observational study was conducted within a single clinical setting over a five-year duration. A total of 117 infertile women underwent assessment using both the 2D/3D HyCoSy and HSG techniques.Participants had a mean age of 27.7 years (standard deviation: 4.2, range: 19-45 years). The diagnostic accuracy of 2D/3D HyCoSy was determined with a sensitivity of 91.86%, specificity of 89.18%, a positive predictive value of 90.40%, and a negative predictive value of 90.82%. Comparative analysis revealed that when evaluating tubal patency in both tubes collectively with HyCoSy, the sensitivity, specificity, and overall accuracy were 91.86%, 89.18%, and 90.59%, respectively. The study findings demonstrated that employing 2D/3D HyCoSy with lignocaine gel proved to be a superior diagnostic approach compared to HSG for assessing tubal patency in women experiencing infertility.