Abstract

Erythropoietin (EPO) is an essential growth factor for red blood cell (RBC) production, and it is mainly produced by renal EPO-producing (REP) cells in the kidneys in an anemia/hypoxia-inducible manner.[1][1],[2][2] Erythropoiesis-stimulating agents (ESAs), including recombinant human EPO (rHuEPO),

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