Abstract
ABSTRACT Objective: The aim of this study was to evaluate the efficacy of two formulations of alprazolam (ALP) in patients undergoing oral implantology surgical procedures. Methods: A single-blinded randomized clinical study was performed with 52 volunteers (both genders) divided into 2 groups: G1 (n = 26) – oral administration of ALP (0.5 mg) 1h before surgical procedures; and G2 (n = 26) – sublingual administration of ALP (0.5mg) 30 minutes before surgery. Blood pressure (BP) and heart rate (HR) were evaluated. Corah dental anxiety scale (COR), visual analogic scale (VAS), Trieger test (TRI) and the perception questionnaire (PQ) were used to assess the level of anxiety and responses to formulations, respectively. All parameters were evaluated at three times (be-fore, during and postoperative). Results: For BP and HR no statistically significant differences were observed between periods for G1 and G2 (p> 0.05). For COR, most volunteers were classi-fied such as anxious or very anxious. For VAS, decreased anxiety was significant (p< 0.05) and no statistically significant differences between the two groups both in the period “pre” (p= 0.18) and “post” (p= 0.12) were observed. For TRI, there were no significant differences between the periods considering the number of points lost (p> 0.05). The anxiety reduction was significant (p< 0.05) for both formulations. As for PQ, both formulations showed good volunteers’ acceptance (p> 0.05), and they have not reported anterograde amnesia. Conclusion: It was concluded that both formulations were effective for sedation of the evaluated volunteers.
Highlights
Fear and anxiety are routine problems in the dental clinic and dental treatment can be considered a crucial problem for odontophobic patients [1]
The type and characteristics of the procedure performed in each group did not present significant differences between the groups leading to sample homogeinity
The result of the patients’ anxiety profile analysis demonstrated the predominance of anxious and very anxious individuals, regardless of age and gender. This corroborates with different authors [7,27,29], who observed a predominance of anxious patients in several dentistry specialties
Summary
Fear and anxiety are routine problems in the dental clinic and dental treatment can be considered a crucial problem for odontophobic patients [1]. Fear of undergoing dental treatments or anxiety about these treatments is called by several authors as dental anxiety or odontophobia [2]. Literature has presented several terms concerning the patient’s acceptance of the dental treatment, such as the fear of the treatment itself and dental anxiety, which is related to the fear of seeking and attending a dental office and phobia [3]. Some subgroups present higher levels than others [4] which may lead to dental appointment avoidance, or yet only seek care in cases of pain [5]. Odontophobic patients may be less cooperative during procedures and present less satisfaction with surgical treatments [6]
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