Abstract

Postmenopausal osteoporosis (PMO) puts women at risk for hip and vertebral fractures, which are associated with a significant increase in morbidity and mortality. While there are a number of potential therapeutic options for the treatment of PMO, bisphosphonates are the treatment of choice. Osteonecrosis of the jaws (ONJ) has been associated with bisphosphonate use predominantly in patients treated with high cumulative drug doses for advanced malignancies. There have been a limited number of ONJ cases in PMO patients, who receive much smaller doses of bisphosphonates.

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