Efficacy and Safety of Topical Botanical Cream in the Treatment of Psoriasis: A Randomized Controlled Study

Abstract

This study evaluated the efficacy and safety of a topical botanical cream containing a combination of herbs for the treatment of psoriasis, a chronic inflammatory skin disease that can considerably diminish the quality of life of a patient. Although numerous topical therapies are available, the majority rely on potentially dangerous steroid creams or coal tar ointments that require a doctor's prescription. In this setting, safe and effective alternative treatments are required. The purpose of this study was to evaluate the efficacy and safety of a topical botanical cream containing a combination of herbs for the treatment of psoriasis.A randomized controlled trial including 51 patients with plaque psoriasis was done. Patients were administered the topical cream for eight consecutive weeks, with the dosage decided by the afflicted skin area. Patients' quality of life was measured using the Psoriasis Disability Index (PDI) and Dermatology Life Quality Index (DLQI).The patients in the therapy group reported a significant reduction in psoriasis severity, as judged by the PASI, according to the study results. The symptoms began to ease as early as the second week of cream use. In addition, as measured by the PDI and DLQI, the patients' quality of life increased. By the sixth week, the DLQI score reduced from a high impact to a moderate impact, while the PDI improved in all categories.The topical botanical cream was proven to be safe and effective in treating psoriasis, hence improving the quality of life of patients. The herbal mixture is a viable alternative to steroid creams and coal tar ointments, which can be used as a substitute or supplement to other standard treatments for psoriasis. To corroborate the outcomes of this trial and determine the long-term safety and efficacy of the botanical cream, however, additional studies with bigger sample sizes are required. This study gives crucial insights into the possible use of herbal formulations in the treatment of psoriasis and highlights the need for additional research in this area.