Abstract
Methods Retrospective study of HIV-1 infected patients in two Genito-Urinary Medicine clinics. Patients taking either Truvada or Kivexa were included. Data including previous treatment, resistance test, HLA B5701 status, pre-treatment CD4 count, plasma viral load, age, ethnicity, renal function, lipid profiles were gathered. Primary endpoint was the proportion of subjects with viral load <50 copies/ ml at 48 weeks.
Highlights
Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1758-2652-11-S1-info.pdf
Limited direct comparative data exist between the recommended dual NRTI fixed dose combinations, tenofovir/ emtricitabine (Truvada) and abacavir/lamivudine (Kivexa)
A recent study (HEAT) evaluated these dual NRTI backbones with a boosted PI
Summary
Address: 1Central Manchester and Manchester Childrens University Hospitals NHS Trust, Manchester, UK and 2University Hospitals of South Manchester NHS Trust, Manchester, UK. Abstracts of the Ninth International Congress on Drug Therapy in HIV Infection Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1758-2652-11-S1-info.pdf
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