Abstract
Propofol is used in most of surgical, endoscopic and colonoscopy procedures which commonly requires general anesthesia, and propofol is one of the most widely used intravenous anesthetics. Propofol is known to have many advantages over other anesthetic agents, including rapid induction of anesthesia, early recovery, and fewer complications such as postoperative nausea and vomiting.1
Highlights
After we reviewed the full texts of 122 potentially relevant articles and reference lists, 30 articles were included in the metaanalysis
Which showed no statistical difference was found between the propofol and other sedative groups OR 0.92; 95% CI 0.81, 1.06; P, 0.01); x2 and I2 were 0.15 (P=0.86) and 0.1%, respectively, indicating the absence of heterogeneity among the studies. (Figure 2)
Subgroup analysis indicated that propofol provided significantly better sedation than traditional sedative agents for Brain trauma and colonoscopy, there was not a significant discrepancy calculated for upper gastrointestinal endoscopy
Summary
|| ISSN(online): 2589-8698 || ISSN(print): 2589-868X || International Journal of Medical and Biomedical Studies. Available Online at www.ijmbs.info NLM (National Library of Medicine ID: 101738825). Index Copernicus Value 2019: 79.34 Volume 5, Issue 3; March: 2021; Page No 56-63. EFFICACY AND SAFETY OF PROPOFOL AS COMPARE TO OTHER ANESTHETICS: A SYSTEMATIC REVIEW AND METAANALYSIS
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