Abstract
ObjectiveIn this meta-analysis, the focus is on investigating the impact of the length of the biliopancreatic limb (BPL) in Roux-en-Y gastric bypass (RYGB) surgery for obesity on the outcomes of weight loss. The objective of this meta-analysis is to assess the influence of long versus standard limb (BPL) interventions on the extent of excess body weight reduction (EBWL) in individuals who have undergone Roux-en-Y gastric bypass (RYGB). IntroductionRoux-en-Y gastric bypass (RYGB) is a procedure commonly used as a treatment for Obesity, the aim of the procedure is to reduce weight and the medical conditions associated with obesity. This study aims to compare the effectiveness and safety of long with short Biliopancreatic limb (BPL). MethodsA systematic review was conducted from PubMed, Cochrane Trial Register, and Google Scholar to identify all the observational studies and randomized controlled trials (RCT) that assessed short and long Biliopancreatic Limb (BPL) in Roux-en-Y gastric bypass (RYGB). The relevant data was analyzed through Review Manager software. ResultsA total of 9 studies were included in the final analysis, out of which 4 were (Randomised Clinical Trial) and 5 were retrospective cohorts. A collective data of 1825 patients were analyzed and reported. The long and short Biliopancreatic Limb ranged from 100 to 200 cm and 30 to 75 cm respectively, and follow-up ranged from 3 to 48 months. Long Biliopancreatic Limb (results in significantly higher % total weight loss and % excess weight loss [MD=1.67, CI=95% (0.93, 2.42), P<0.0001], [MD=6.39, CI=95% (5.00, 7.79), P<0.00001] respectively. In addition, patients with long Biliopancreatic Limb experienced significantly more Body Mass Index (BMI) change [MD=0.52, CI=95%, P=0.004]. Both Short and Long Biliopancreatic Limb had similar early complication rates [RR=1.15, 95% CI (0.79, 1.69), P=0.47]. ConclusionIn conclusion, this meta-analysis underscores the significant influence of biliopancreatic limb (BPL) length in Roux-en-Y gastric bypass (RYGB) surgery on outcomes of weight loss among individuals with obesity. The findings consistently highlight that longer BPL interventions contribute to greater excess body weight reduction (EBWL) compared to standard limb lengths. This suggests that careful consideration of BPL length in RYGB procedures can optimize weight loss outcomes, providing valuable insights for clinical practice and further research in bariatric surgery.
Published Version
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