Abstract
J Maloney, DI Bernstein, H Nelson. Ann Allergy Asthma Immunol. 2014;112(2):146–153.e2 The goal of this study was to evaluate the safety and efficacy of treatment with a grass sublingual immunotherapy tablet (MK-7243) in children and adults with allergic rhinoconjunctivitis. Previous studies have been conducted outside of North America and have included only sparse pediatric data. Studied were 1501 North American subjects aged 5 to 65 years. The study included 283 children with a physician-diagnosed history of grass pollen–induced allergic rhinoconjunctivitis, with or without asthma, who had received treatment of their symptoms during the previous grass pollen season. Inclusion criteria were positive skin prick test response to Phleum pratense (≥5-mm wheal); positive specific IgE against P pratense …
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