Abstract
Aim. To study of efficacy and safety of glycoprotein IIb/IIIa blocker monafram in acute ST-segment elevation myocardial infarction (STEMI) patients, underwent coronary stenting. Material and methods. 220 STEMI patients were included in the trial; they were split into two groups. 109 patients of the first group were underwent coronary stenting with i/v monafram therapy. Coronary stenting without monafram therapy was performed in 111 patients of the second group. Bare metal stents were used in all patients. Deaths, stent thrombosis, individual intolerance, allergic reactions, bleeding were registered during hospitalization. Results. There were 3 (2.75%) cases of stent thrombosis in monafram group and 4 (3.6%) ones - in the control group. Good tolerance of monafram was observed in all patients. There were no allergic reactions, major and minor bleedings. Reinfarction rate was similar in both groups during 30 days observational period. Conclusions. Monafram therapy is effective and safe in acute STEMI patients underwent coronary stenting.
Highlights
ЭФФЕКТИВНОСТЬ И БЕЗОПАСНОСТЬ БЛОКАТОРА ГЛИКОПРОТЕИНОВЫХ РЕЦЕПТОРОВ IIB/IIIА МОНАФРАМА ПРИ КОРОНАРНОМ СТЕНТИРОВАНИИ ПАЦИЕНТОВ С ОСТРЫМ ИНФАРКТОМ МИОКАРДА
Эффективность и безопасность блокатора гликопротеиновых рецепторов IIb/IIIа монофрама при коронарном стентировании пациентов с острым инфарктом миокарда Э.И.
Изучить эффективность и безопасность блокатора гликопротеиновых рецепторов IIb/IIIа монафрама у больных острым инфарктом миокарда с подъемом сегмента ST (ОИМ СПсST), перенесших коронарное стентирование.
Summary
ЭФФЕКТИВНОСТЬ И БЕЗОПАСНОСТЬ БЛОКАТОРА ГЛИКОПРОТЕИНОВЫХ РЕЦЕПТОРОВ IIB/IIIА МОНАФРАМА ПРИ КОРОНАРНОМ СТЕНТИРОВАНИИ ПАЦИЕНТОВ С ОСТРЫМ ИНФАРКТОМ МИОКАРДА Эффективность и безопасность блокатора гликопротеиновых рецепторов IIb/IIIа монофрама при коронарном стентировании пациентов с острым инфарктом миокарда Э.И. Изучить эффективность и безопасность блокатора гликопротеиновых рецепторов IIb/IIIа монафрама у больных острым инфарктом миокарда с подъемом сегмента ST (ОИМ СПсST), перенесших коронарное стентирование.
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